<div class="snap-chik-content"> <p>Chromatin modifying enzymes target specific histone residues for post-translational modification, including methylation, acetylation, phosphorylation. As such, these proteins drive major changes in chromatin structure, and are important targets in academic and pharmaceutical research. EpiCypher offers a library of histone methyltransferase enzymes and catalytic domains, each highly pure and validated for on-target substrates.</p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/recombinant-proteins/modifying-enzymes/#modifyenz" class="button snap-chip-custom-btn">Shop Modifying Enzymes</a> </div> <p></p> <h5>Applications for chromatin modifying enzymes</h5> <ul> <li>Inhibitor assays<a href="/content/documents/technotes/NSD2_AlphaNuc.pdf/"> (see our AlphaNuc™ platform).</a></li> <li>Methyltransferase assays<a href="/content/documents/brochures/EpiCypher_dCypher.pdf/"> (see our dCypher® platform).</a></li> </ul> <h5>Learn more:</h5> <ul> <li>Interested in profiling chromatin reader binding specificity?<a href="/content/documents/technotes/dCypher_TechNote.pdf/"> Click here for more info on dCypher!</a></li> <li>Need an assay to study chromatin remodeling enzymes?<a href=" /blog/epidyne-exploring-chromatin-remodeling-substrates-with-nucleosomes/"> Read about EpiDyne® on our Blog</a></li> <li>Getting started with EpiDyne? <a href="/content/documents/technotes/EpiDyne_FRET.pdf/"> Be sure to check out our Tech Note</a></li> </ul> <h5> Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/dcypher-assay-services-for-novel-chromatin-interactions/">dCypher Assay Services</a></li> <li><a href="/epidyne-chromatin-remodeling-enzymes/">EpiDyne Chromatin Remodeling Enzymes</a></li> </ul> <a name="modifyenz"></a>

DOT1L Catalytic Domain, Recombinant Human
SKU: 15-1001
Type:  HMT Host:  E. coli Mol Wgt.:  85 kDa Epitope Tag:  GST Recombinant DOT1L Catalytic Domain Enzyme Description: Recombinant human DOT1 protein, catalytic domain (DOT1L, KMT4, accession...
$305.00
G9a, Recombinant Human, His-tagged
SKU: 15-1010
Type:  HMT Host:  E. coli Mol Wgt.:  39 kDa Epitope Tag:  6xHis G9a, Recombinant Human, His-tagged Enzyme Description: Recombinant human G9a protein, (EHMT2 BAT8, KMT1C, accession Q96KQ7,...
$305.00
NSD2 / MMSET Catalytic Domain, Recombinant Human
SKU: 15-1002
Type:  HMT Host:  E. coli Mol Wgt.:  61 kDa Epitope Tag:  GST NSD2 / MMSET Catalytic Domain, Recombinant Human Description: NSD2 / MMSET Catalytic Domain, Recombinant Human (WHSC1,...
$305.00
SETD2, Recombinant Human
SKU: 15-1012
Type:  HMT Host:  E. coli Mol Wgt.:  43 kDa Epitope Tag:  by product SETD2, Recombinant Human Enzyme Description: SETD2, Recombinant Human (SET2, HYPB, HIF1, KMT3A,...
$305.00
SETD2, Recombinant Human GST-tagged
SKU: 15-1011
Type:  HMT Host:  E. coli Mol Wgt.:  68 kDa Epitope Tag:  GST SETD2, Recombinant Human GST-tagged Enzyme Description: SETD2, Recombinant Human GST-tagged protein (SET2,...
$305.00
SETD6, Recombinant Human
SKU: 15-1004
Type:  HMT Host:  E. coli Mol Wgt.:  72 kDa Epitope Tag:  GST Recombinant SETD6 Enzyme Description: Recombinant full-length human SETD6 protein (SET6, accession Q8TBK2, amino acids 1-473),...
$305.00
SMYD2, Recombinant Human
SKU: 15-1006
Type:  HMT Host:  E. coli Mol Wgt.:  68 kDa Epitope Tag:  GST Recombinant SMYD2 Enzyme Description: Recombinant full-length human SMYD2 protein, (KMT3C, accession Q9NRG4), containing an...
$230.00
SMYD3, Recombinant Human
SKU: 15-1007
Type:  HMT Host:  E. coli Mol Wgt.:  68 kDa Epitope Tag:  GST Recombinant SMYD3 Enzyme Description: Recombinant full-length human SMYD3 protein, (SET and MYND domain-containing protein 3,...
$230.00