Histone variants have important roles across diverse cellular processes, including DNA replication, DNA repair, and transcriptional regulation. EpiCypher variant nucleosomes (vNucs) are assembled with defined histone variants, providing a physiological substrate for the functional analysis of these non-canonical nucleosomes.
<div class="snap-chik-content"> <p>Histone variants have important roles across diverse cellular processes, including DNA replication, DNA repair, and transcriptional regulation. EpiCypher variant nucleosomes (vNucs) are assembled with defined histone variants, providing a physiological substrate for the functional analysis of these non-canonical nucleosomes.</p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/nucleosomes/variant-nucleosomes-vnucs-1/#vnucsprods" class="button snap-chip-custom-btn">Shop vNucs</a> </div> <p></p> <h5>Three ways to leverage vNucs for chromatin research</h5> <ul> <li>Use as substrates for testing for inhibitors</li> <li>Study effects of variant histone on enzyme activity</li> <li>Test specificity of antibody</li> </ul> <h5>Learn more:</h5> <ul> <li><a href="/content/documents/brochures/rnucs.pdf/">Recombinant Nucleosomes Brochure</a></li> <li>How can recombinant nucleosomes be used to study chromatin interactions? <a href="/content/documents/technotes/dCypher_TechNote.pdf/">See our dCypher Tech Note</a></li> <li>Why should you use nucleosomes vs. modified histone peptides? <a href="/blog/peptide-or-nucleosome-dcypher-reveals-the-optimal-substrate-for-histone-ptm-analyses/">Read our Blog for more info!</a></li> </ul> <h5>Shop related products</h5> <ul class="category-nav-list"> <li><a href="/recombinant-nucleosomes/"> All Nucleosomes</a></li> <li><a href="/nucleosomes/dcypher-nucleosome-panels/">dCypher® Nucleosome Panels</a></li> </ul> <a name="vnucsprods"></a>
