$550.00
EpiDyne® Chromatin Remodeling Enzymes
ATP-dependent chromatin remodeling enzymes are among the most commonly mutated proteins in cancer, making them a top target for the development of novel therapeutic strategies. The EpiDyne® platform leverages EpiCypher dNucs as substrates to study nucleosome remodeling. To complement these assays, EpiCypher offers a range of remodeling enzymes, including SMARCA2 and SMARCA4 (the ATPases of the SWI/SNF complex) and the ACF ISWI-type complex.
EpiDyne : advanced tools for next-generation epigenetics assays
EpiDyne Chromatin Remodeling Enzymes can be used in a variety of assay readouts, including:
- FRET (read Tech Note here) – HTS compatible
- Radiometric DAM methyltransferase assays – HTS compatible
- Restriction enzyme accessibility (read Tech Note here)
Learn more:
- EpiDyne Brochure
- Read more about the EpiDyne platform on the EpiCypher Blog!
- Getting started with EpiDyne? Be sure to check out our Tech Note
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