EpiDyne^® Chromatin Remodeling Enzymes

ATP-dependent chromatin remodeling enzymes are among the most commonly mutated proteins in cancer, making them a top target for the development of novel therapeutic strategies. The EpiDyne® platform leverages EpiCypher dNucs as substrates to study nucleosome remodeling. To complement these assays, EpiCypher offers a range of remodeling enzymes, including SMARCA2 and SMARCA4 (the ATPases of the SWI/SNF complex) and the ACF ISWI-type complex.

Shop EpiDyne Remodeling Enzymes

EpiDyne : advanced tools for next-generation epigenetics assays

EpiDyne Chromatin Remodeling Enzymes can be used in a variety of assay readouts, including:

FRET (read Tech Note here) – HTS compatible
Radiometric DAM methyltransferase assays – HTS compatible
Restriction enzyme accessibility (read Tech Note here)

Learn more:

EpiDyne Brochure
Read more about the EpiDyne platform on the EpiCypher Blog!
Getting started with EpiDyne? Be sure to check out our Tech Note

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SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SKU: 15-1024

Species: Human Source: SF9 cells Epitope Tag: FLAG-6His Mol Wgt: 123.7 kDa Description ...

$405.00

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SKU: 15-1014

Species: Human Source: SF9 cells Epitope Tag: 6xHis-FLAG Mol Wgt: 186.6 kDa Description ...

$550.00

SMARCA2 Chromatin Remodeling Enzyme Human BRM

SMARCA2 Chromatin Remodeling Enzyme (Human BRM)

SKU: 15-1015

Species: Human Source: SF9 cells Epitope Tag: 6His-FLAG Mol Wgt: 181 kDa Description ...

$550.00

ACF Chromatin Remodeling Enzyme Complex

ACF Chromatin Remodeling Enzyme Complex

SKU: 15-1013

...

$505.00