Modifying Enzymes

Chromatin modifying enzymes target specific histone residues for post-translational modification, including methylation, acetylation, phosphorylation. As such, these proteins drive major changes in chromatin structure, and are important targets in academic and pharmaceutical research. EpiCypher offers a library of histone methyltransferase enzymes and catalytic domains, each highly pure and validated for on-target substrates.

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Applications for chromatin modifying enzymes

Inhibitor assays (see our AlphaNuc™ platform).
Methyltransferase assays (see our dCypher™ platform).

Learn more:

Interested in profiling chromatin reader binding specificity? Click here for more info on dCypher™!
Need an assay to study chromatin remodeling enzymes? Read about EpiDyne® on our Blog
Getting started with EpiDyne? Be sure to check out our Tech Note

Shop related products and services:

SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SKU: 15-1024

Species: Human Source: SF9 cells Epitope Tag: FLAG-6His Mol Wgt: 123.7 kDa Description ...

$405.00

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SKU: 15-1014

Species: Human Source: SF9 cells Epitope Tag: 6xHis-FLAG Mol Wgt: 186.6 kDa Description ...

$575.00

SMARCA2 Chromatin Remodeling Enzyme Human BRM

SMARCA2 Chromatin Remodeling Enzyme (Human BRM)

SKU: 15-1015

Species: Human Source: SF9 cells Epitope Tag: 6His-FLAG Mol Wgt: 181 kDa Description ...

$575.00

ACF Chromatin Remodeling Enzyme Complex

ACF Chromatin Remodeling Enzyme Complex

SKU: 15-1013

...

$505.00

5x SMARCA Remodeling Assay Buffer

5x SMARCA Remodeling Assay Buffer

SKU: 21-0014

...

$55.00

5x ACF Remodeling Assay Buffer

5x ACF Remodeling Assay Buffer

SKU: 21-0013

...

$55.00