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    • Nucleosomes
    • EpiDyne® Chromatin Remodeling Substrates

    EpiDyne® Chromatin Remodeling Substrates

    Chromatin remodeling has been implicated in diverse diseases, including most types of cancer. The study of chromatin remodeling requires highly defined nucleosomal substrates, which are challenging to produce and adapt to various assays. The EpiDyne® platform addresses this unmet need, leveraging EpiCypher dNucs™ as substrates for a variety of nucleosome remodeling assays.

    Shop EpiDyne Substrates

    EpiDyne substrates are suitable for various chromatin remodeling assays
    • EpiDyne-FRET: HTS compatible, ideal for compound screening
    • EpiDyne-PicoGreen: proprietary method, enables high throughput at low cost
    • Restriction Enzyme Accessibility (REA) also supported
    • Full details and protocols available in User Guide
    Learn more:
    • EpiDyne Brochure
    • Getting started with EpiDyne? Read the User Guide
    • Learn about EpiDyne applications on our Blog
    • How do we quantify our nucleosomes? See our Nucleosome Quantification Method
    Shop related products and services:
    • EpiDyne Remodeling Enzymes
    • EpiDyne HTS Services
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0, Biotinylated
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0, Biotinylated
    SKU: 18-4110
    Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...
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    $115.00
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, 50-N-66, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, 50-N-66, Biotinylated
    SKU: 16-4116
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, 50-N-66, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession...
    View
    $565.00
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2, 50-N-66, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2, 50-N-66, Biotinylated
    SKU: 16-4115
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2, 50-N-66, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession...
    View
    $565.00
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1, 50-N-66, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1, 50-N-66, Biotinylated
    SKU: 16-4114
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1, 50-N-66, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers:...
    View
    $565.00
    EpiDyne-FRET Nucleosome Remodeling Assay Substrate
    EpiDyne-FRET Nucleosome Remodeling Assay Substrate
    SKU: 16-4201
    Description This product provides a high throughput fluorescent readout of nucleosome remodeling when paired with enzymatically active remodeling complexes, such as SMARCA4,...
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    $595.00
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1, Biotinylated
    SKU: 16-4111
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers:...
    View
    $565.00
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1
    SKU: 16-4101
    Description Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers: H2A-P04908;...
    View
    $565.00
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2, Biotinylated
    SKU: 16-4112
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers:...
    View
    $565.00
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, Biotinylated
    EpiDyne® Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3, Biotinylated
    SKU: 16-4113
    EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1,2,3 Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers:...
    View
    $565.00
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0
    SKU: 18-4100
    EpiDyne Remodeling Assay Substrate DNA ST601-GATC0 Description: EpiDyne Remodeling Assay Substrate DNA...
    View
    $115.00
    EpiDyne Remodeling Assay Substrate DNA ST601-GATC1,2, Biotinylated
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1,2, Biotinylated
    SKU: 18-4112
    EpiDyne Remodeling Assay Substrate DNA ST601-GATC1,2, Biotinylated Description: EpiDyne Remodeling Assay Substrate DNA ST601-GATC1,2, Biotinylated is a 217 base-pair double-stranded DNA fragment containing a 5' biotin-TEG group. This sequence...
    View
    $115.00
    EpiDyne-FRET Remodeling Assay Substrate DNA
    EpiDyne-FRET Remodeling Assay Substrate DNA
    SKU: 18-4201
    View
    $165.00
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1
    SKU: 18-4101
    Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...
    View
    $115.00
    EpiDyne Remodeling Assay Substrate DNA ST601-GATC1, Biotinylated
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1, Biotinylated
    SKU: 18-4111
    Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...
    View
    $115.00
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1,2,3, Biotinylated
    EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1,2,3, Biotinylated
    SKU: 18-4113
    EpiDyne Remodeling Assay Substrate DNA ST601-GATC1,2,3, Biotinylated Description: EpiDyne Remodeling Assay Substrate DNA ST601-GATC1,2,3, Biotinylated is a 217 base-pair double-stranded DNA fragment containing a 5' biotin-TEG group. This...
    View
    $115.00
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      • Products dropdown_arrow
      • EpiCypher 2023 Conference Test
      • Test CUT&RUN Complete Guide
      • Servicesdropdown_arrow
        • Services
        • EpiDyne Chromatin Remodeling HTS assays
        • Custom Nucleosome Development Services
        • dCypher™ Assay Services For Novel Chromatin Interactions
        • SNAP-ChIP Antibody Validation Services
      • Technologiesdropdown_arrow
        • Technologies
        • CUTANA™ Assays Overview
        • CUTANA™ CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
        • SNAP Spike-in Controls
        • SNAP-Certified™ Antibodies
      • Resourcesdropdown_arrow
        • Resources
        • Blog
        • Protocols
        • Product References
        • Tech Support Center
        • Technical Notes (Tech Notes)
        • Product Brochures
        • Scientific Posters
        • Epigenetics Conferences
        • EpiCypher 2023 Conference
      • Aboutdropdown_arrow
        • About
        • About EpiCypher
        • Management
        • Board of Directors
        • Scientific Founders
        • Press Releases
        • Join Our Team
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      • Terms of Use
      • Products
      • Nucleosomesdropdown_arrow
        • Nucleosomes
        • Recombinant Nucleosomes (Complete List)
        • SNAP-ChIP® Spike-ins
        • SNAP-CUTANA™ Spike-in Controls
        • Modified Designer Nucleosomes (dNucs™)
        • dCypher™ Nucleosome Panels
        • EpiDyne® Chromatin Remodeling Substrates
        • Recombinant Nucleosomes (rNucs)
        • Mutant Nucleosomes
        • Purified Nucleosomes (HeLa, Avian)
        • Nucleosome Components and Subunits
        • Variant Nucleosomes (vNucs)
        • Methyl DNA Designer Nucleosomes
      • Antibodiesdropdown_arrow
        • Antibodies
        • Antibodies (Complete List)
        • CUTANA™ CUT&RUN Antibodies
        • CUTANA™ CUT&Tag Antibodies
        • SNAP-ChIP® Certified Antibodies
      • Epigenetics Kits and Reagentsdropdown_arrow
        • Epigenetics Kits and Reagents
        • CUTANA™ ChIC / CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
        • Cell Extracts
      • Recombinant Proteinsdropdown_arrow
        • Recombinant Proteins
        • EpiDyne® Chromatin Remodeling Enzymes
        • Recombinant Histones
        • Histone Binding Domains
        • Modifying Enzymes
      • Otherdropdown_arrow
        • Other
        • IDEA Toolbox
        • Histone Peptides
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