<div class="snap-chik-content"> <p> Chromatin remodeling has been implicated in diverse diseases, including most types of cancer. The study of <strong>chromatin remodeling </strong>requires highly defined nucleosomal substrates, which are challenging to produce and adapt to various assays. The EpiDyne® platform addresses this unmet need, leveraging EpiCypher dNucs™ as substrates for a variety of nucleosome remodeling assays. </p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/epidyne-chromatin-remodeling-substrates/#epidynenucs" class="button snap-chip-custom-btn">Shop EpiDyne Substrates</a> </div> <p></p> <h5> EpiDyne substrates are available for three assay readouts</h5> <ul> <li>FRET <a href="/content/documents/technotes/EpiDyne_FRET.pdf/">(read Tech Note here)</a> – HTS compatible</li> <li>Radiometric DAM methyltransferase assays – HTS compatible</li> <li>Restriction enzyme accessibility <a href="/content/documents/technotes/EpiDyne_REA.pdf/">(read Tech Note here)</a></li> </ul> <h5>Learn more:</h5> <ul> <li><a href="/content/documents/brochures/EpiDyne.pdf/"> EpiDyne Brochure</a></li> <li>Getting started with EpiDyne? <a href="/content/documents/technotes/EpiDyne_FRET.pdf/">Read our Tech Note!</a></li> <li>Learn about EpiDyne applications on <a href=" /blog/epidyne-exploring-chromatin-remodeling-substrates-with-nucleosomes/">our Blog</a></li> </ul> <h5> Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/epidyne-chromatin-remodeling-enzymes/">EpiDyne Remodeling Enzymes</a></li> <li><a href="/epidyne-chromatin-remodeling-hts-assays/">EpiDyne HTS Services</a></li> </ul> <a name="epidynenucs"></a>

EpiDyne-FRET Nucleosome Remodeling Assay Substrate
SKU: 16-4201
EpiDyne-FRET Nucleosome Remodeling Assay Substrate Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A-Cy5, H2B, H3.2 and H4; accession numbers: H2A-P04908; H2B-O60814;...
$575.00
EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1
SKU: 16-4101
EpiDyne Nucleosome Remodeling Assay Substrate ST601-GATC1 Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4. Accession numbers: H2A-P04908;...
$525.00
EpiDyne Remodeling Assay Substrate DNA ST601-GATC0
SKU: 18-4100
EpiDyne Remodeling Assay Substrate DNA ST601-GATC0 Description: EpiDyne Remodeling Assay Substrate DNA ST601-GATC0 is a 217 base-pair double-stranded DNA fragment. This sequence includes the Lowary 601 nucleosome positioning sequence (see...
$105.00
EpiDyne Remodeling Assay Substrate DNA ST601-GATC1
SKU: 18-4101
EpiDyne Remodeling Assay Substrate DNA ST601-GATC1 Description: EpiDyne Remodeling Assay Substrate DNA ST601-GATC1 is a 217 base-pair double-stranded DNA fragment. This sequence includes the Lowary 601 nucleosome positioning sequence (see...
$105.00