<div class="snap-chik-content"> <p>ATP-dependent chromatin remodeling enzymes are among the most commonly mutated proteins in cancer, making them a top target for the development of novel therapeutic strategies. The EpiDyne® platform leverages EpiCypher dNucs as substrates to study nucleosome remodeling. To complement these assays, EpiCypher offers a range of remodeling enzymes, including SMARCA2 and SMARCA4 (the ATPases of the SWI/SNF complex) and the ACF ISWI-type complex.</p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/epidyne-chromatin-remodeling-enzymes/#epienzymes" class="button snap-chip-custom-btn">Shop EpiDyne Remodeling Enzymes</a> </div> <p></p> <h5> EpiDyne : advanced tools for next-generation epigenetics assays </h5> <p> EpiDyne Chromatin Remodeling Enzymes can be used in a variety of assay readouts, including:<p> <ul> <li>FRET <a href="/content/documents/technotes/EpiDyne_FRET.pdf/">(read Tech Note here)</a> – HTS compatible</li> <li>Radiometric DAM methyltransferase assays – HTS compatible</li> <li>Restriction enzyme accessibility <a href="/content/documents/technotes/EpiDyne_REA.pdf/">(read Tech Note here)</a></li> </ul> <h5>Learn more:</h5> <ul> <li><a href="/content/documents/epidyne_brochure.pdf/">EpiDyne Brochure</a></li> <li>Read more about the EpiDyne platform on <a href=" /blog/epidyne-exploring-chromatin-remodeling-substrates-with-nucleosomes/">the EpiCypher Blog!</a></li> <li>Getting started with EpiDyne? <a href="/content/documents/technotes/EpiDyne_FRET.pdf/">Be sure to check out our Tech Note</a></li> </ul> <h5> Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/epidyne-chromatin-remodeling-substrates/">EpiDyne Chromatin Remodeling Substrates</a></li> <li><a href="/epidyne-chromatin-remodeling-hts-assays/">EpiDyne HTS Services</a></li> </ul> <a name="epienzymes"></a>