SKU: 15-1015
{"AddThisServiceButtonMeta":"","add_this":[{"annotation":"","service":"facebook"},{"annotation":"","service":"email"},{"annotation":"","service":"print"},{"annotation":"","service":"twitter"},{"annotation":"","service":"linkedin"}],"add_to_wishlist_url":"/wishlist.php?action=add&product_id=650","availability":"","bulk_discount_rates":[],"can_purchase":true,"cart_url":"https://www.epicypher.com/cart.php","category":["Nucleosomes/EpiDyne® Chromatin Remodeling Substrates/EpiDyne<sup>®</sup> Modifying Enzymes ","Recombinant Proteins/EpiDyne<sup>®</sup> Chromatin Remodeling Enzymes","Recombinant Proteins/Modifying Enzymes"],"custom_fields":[{"id":"1081","name":"Pack Size","value":"100 Reactions"},{"id":"1082","name":"Internal Comment","value":"extra in top right of Psylocke"}],"customizations":[],"description":"<div class=\"product-general-info\">\n <ul class=\"product-general-info__list-left\">\n <li class=\"product-general-info__list-item\">\n <strong>Type: </strong>Remodeler/ATPase\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Mol Wgt: </strong>181 kDa\n </li>\n </ul>\n <ul class=\"product-general-info__list-right\">\n <li class=\"product-general-info__list-item\">\n <strong>Expressed In: </strong>SF9 cells\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Epitope Tag: </strong>FLAG\n </li>\n </ul>\n</div>\n<div class=\"service_accordion product-droppdown\">\n <div class=\"container\">\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Description</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n style=\"display: block\"\n >\n <p>\n Enzymatically active, full length recombinant human SMARCA2\n Remodeling Enzyme (BRM, UniProt reference no. P51531-2) produced in\n SF9 cells. SMARCA2 is the catalytic subunit of the SWI/SNF complex.\n It is an ATP-dependent chromatin remodeling enzyme that regulates\n nucleosome spacing.\n </p>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Validation Data</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n style=\"display: block\"\n >\n <section class=\"image-picker\">\n <div class=\"image-picker__left\">\n <div\n class=\"image-picker__main-content_active image-picker__main-content\"\n >\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-1015-chromatin-remodeling-assay.jpeg\"\n target=\"blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-1015-chromatin-remodeling-assay\"\n src=\"/content/images/products/proteins/15-1015-chromatin-remodeling-assay.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong\n >Figure 1: ATP-dependent chromatin remodeling assay </strong\n ><br />EpiDyne<sup>®</sup>-FRET Chromatin Remodeling\n Substrate (EpiCypher\n <a\n href=\"/products/nucleosomes/epidyne-fret-nucleosome-remodeling-assay-substrate\"\n >16-4201</a\n >; 15nM) incubated with SMARCA2 Remodeling Enzyme\n (concentrations indicated) in 1x SMARCA2 Remodeling Assay\n Buffer. Curves denote FRET efficiency/chromatin remodeling.\n </span>\n </p>\n </div>\n <div class=\"image-picker__main-content\">\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-1015-protein-gel-data.jpeg\"\n target=\"blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-1015-protein-gel-data\"\n src=\"/content/images/products/proteins/15-1015-protein-gel-data.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong>Figure 2: Protein gel data </strong><br />\n SMARCA2 Remodeling Enzyme (1 µg) was run on an SDS-PAGE gel\n and stained with Coomassie blue. The migration and molecular\n weight of the protein standards are indicated.\n </span>\n </p>\n </div>\n </div>\n <aside class=\"image-picker__right\">\n <div class=\"image-picker__gallery\">\n <img\n alt=\"15-1015-chromatin-remodeling-assay\"\n src=\"/content/images/products/proteins/15-1015-chromatin-remodeling-assay.jpeg\"\n width=\"200\"\n class=\"image-picker__side-image image-picker__side-image_active\"\n role=\"button\"\n />\n <img\n alt=\"15-1015-protein-gel-data\"\n src=\"/content/images/products/proteins/15-1015-protein-gel-data.jpeg\"\n class=\"image-picker__side-image\"\n role=\"button\"\n />\n </div>\n </aside>\n </section>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Technical Information</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-tech-info\">\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Formulation:</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n SMARCA2 in 25 mM HEPES pH 7.6, 300 mM NaCl, 0.1 mM EDTA, 10%\n glycerol, 1 mM DTT, 0.4 mM PMSF, 0.1 mM benzamidine, 0.4 mg/mL\n recombinant human insulin.\n </div>\n </div>\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Storage and Stability:</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n Stable for six months -80°C from date of receipt. For best\n results, aliquot and avoid multiple freeze/thaws.\n </div>\n </div>\n </div>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Application Notes</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <p>\n This product is sufficient to perform 100 remodeling reactions using\n EpiDyne<sup>®</sup>-FRET substrate (EpiCypher\n <a\n href=\"/products/nucleosomes/epidyne-fret-nucleosome-remodeling-assay-substrate\"\n >16-4201</a\n >). A single reaction is defined as 10 µL containing [20 nM SMARCA2,\n 20 nM EpiDyne<sup>®</sup>-FRET, 1 mM rATP] and remodels to\n completion in <30 minutes. 5x SMARCA Remodeling Assay Buffer is\n included (EpiCypher\n <a\n href=\"/products/recombinant-proteins/modifying-enzymes/5x-smarca-remodeling-assay-buffer\"\n >21-0014</a\n >). For more information, see the\n <a href=\"/resources/technical-notes/\"\n >EpiDyne<sup>®</sup>-FRET Technote</a\n >\n or contact\n <a href=\"mailto:techsupport@epicypher.com\"\n >techsupport@epicypher.com</a\n >.\n </p>\n </div>\n </div>\n </div>\n\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Documents & Resources</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-documents\">\n <a\n href=\"/content/documents/tds/15-1015.pdf\"\n target=\"blank\"\n class=\"product-documents__link\"\n >\n <svg\n version=\"1.1\"\n id=\"Layer_1\"\n xmlns=\"http://www.w3.org/2000/svg\"\n xmlns:xlink=\"http://www.w3.org/1999/xlink\"\n x=\"0px\"\n y=\"0px\"\n viewBox=\"0 0 228 240\"\n style=\"enable-background: new 0 0 228 240\"\n xml:space=\"preserve\"\n class=\"product-documents__icon\"\n >\n <g>\n <path\n class=\"product-documents__svg-pdf\"\n 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c2.02,3.63,3.04,7.98,3.04,13.04c0,5.06-1,9.42-3,13.08c-2,3.66-4.91,6.45-8.73,8.38c-3.82,1.93-8.4,2.9-13.73,2.9H69.92V125.68z\n M88.07,165.63c10.35,0,15.52-5.22,15.52-15.66c0-10.4-5.17-15.59-15.52-15.59h-7.38v31.26H88.07z\"\n />\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M122.57,125.68h32.84v8.49h-22.22v11.18h20.84v8.49h-20.84v20.49h-10.63V125.68z\"\n />\n </g>\n </svg>\n <span class=\"product-documents__info\">Technical Datasheet</span>\n </a>\n </div>\n </div>\n </div>\n </div>\n </div>\n</div>\n","detail_messages":"","gift_wrapping_available":false,"gtin":null,"id":"650","images":[{"alt":"SMARCA2 Chromatin Remodeling Enzyme Human BRM","data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/650/953/smarca2-chromatin-remodeling-enzyme-human-brm__84445.1645734545.jpg?c=2"}],"main_image":{"alt":"SMARCA2 Chromatin Remodeling Enzyme Human 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","url":"https://www.epicypher.com/products/nucleosomes/epidyne-chromatin-remodeling-substrates/epidyne-modifying-enzymes/acf-chromatin-remodeling-enzyme-complex","weight":{"formatted":"0.01 LBS","value":0.01}},{"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=651","add_to_wishlist_url":"/wishlist.php?action=add&product_id=651","availability":"","brand":{"name":null},"category":["Nucleosomes/EpiDyne® Chromatin Remodeling Substrates/EpiDyne<sup>®</sup> Modifying Enzymes ","Recombinant Proteins/EpiDyne<sup>®</sup> Chromatin Remodeling Enzymes","Recombinant Proteins/Modifying Enzymes"],"custom_fields":[{"id":1020,"name":"Pack size","value":"100 reactions"},{"id":1021,"name":"Internal Comment","value":"Bulk in Bulk Protein Box, top right of Psylocke"},{"id":1022,"name":"Internal Comment","value":"Lot 7 aliquots in Harley Quinn"},{"id":1023,"name":"Internal Comment","value":"21-1014 is sold with this item."}],"date_added":"15th Feb 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Pack Size: 100 Reactions
