Chromatin architecture is composed of a diverse array of histone PTMs, which influence gene expression via the binding activity of various chromatin reader proteins. These proteins contain binding domains that target specific histone PTMs, and are important subjects in academic and pharmaceutical research. EpiCypher® offers a wide range of recombinant GST-tagged histone binding domains, including chromodomains and bromodomains, which can be used in a variety of downstream applications.
<div class="snap-chik-content"> <p> Chromatin architecture is composed of a diverse array of histone PTMs, which influence gene expression via the binding activity of various chromatin reader proteins. These proteins contain binding domains that target specific histone PTMs, and are important subjects in academic and pharmaceutical research. EpiCypher® offers a wide range of recombinant GST-tagged histone binding domains, including chromodomains and bromodomains, which can be used in a variety of downstream applications.</p> <div class="custom-btns-block"> <a href="#histbinddomains" class="button snap-chip-custom-btn">Shop Histone Binding Domains</a> </div> <p></p> <h5>EpiCypher histone PTM binding domains</h5> <ul> <li><a href="/recombinant-histone-binding-domains/bromodomain-proteins-1/">Bromodomain Proteins </a>: Histone Acetylation </li> <li> <a href="/recombinant-histone-binding-domains/yeats-domain-proteins-1/">YEATs Proteins</a> : Histone Acylation</li> <li> <a href="/recombinant-proteins/histone-binding-domains/chromodomain-proteins/">Chromodomain Proteins</a> : Histone Methylation</li> <li> <a href="/recombinant-histone-binding-domains/phd-domain-proteins-1/">PHD domain proteins</a> : Histone Methylation</li> <li> <a href="/recombinant-histone-binding-domains/mbt-domain-proteins-1/">MBT domain proteins</a> : Histone Methylation</li> </ul> <h5>Learn more:</h5> <ul> <li>Nucleosomes vs. modified histone peptides : which is better for chromatin research? <a href="/blog/peptide-or-nucleosome-dcypher-reveals-the-optimal-substrate-for-histone-ptm-analyses/">Read our Blog for more info</a></li> <li>Interested in using nucleosomes to examine chromatin reader interactions? <a href= "/content/documents/brochures/EpiCypher_dCypher.pdf/ ">Click here to learn about dCypher®!</a></li> </ul> <h5>Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/recombinant-nucleosomes/">All Nucleosomes</a></li> <li><a href="/dcypher-assay-services-for-novel-chromatin-interactions/">dCypher® Screening Services</a></li> </ul> <a name="histbinddomains"></a>
