Histone Binding Domains

Chromatin reader proteins bind specific histone modifications and often recruit additional proteins, enzymes, or regulatory complexes. They play vital roles in many disease-relevant pathways and represent key drug targets. EpiCypher offers a variety of recombinant GST-tagged histone binding domains for academic and pharmaceutical research.

Shop Histone Binding Domains

EpiCypher histone PTM binding domains

Bromodomain Proteins : Histone Acetylation
YEATS Proteins : Histone Acylation
Chromodomain Proteins : Histone Methylation

Learn more:

dCypher assays screen proteins against nucleosomes to identify novel interactions. Read our blog to learn more
If your project requires specialized substrates, see our custom nucleosome assembly services
Trying to set up dCypher assays in your lab? Check out our detailed tech notes