Histone Binding Domains

Chromatin architecture is composed of a diverse array of histone PTMs, which influence gene expression via the binding activity of various chromatin reader proteins. These proteins contain binding domains that target specific histone PTMs, and are important subjects in academic and pharmaceutical research. EpiCypher® offers a wide range of recombinant GST-tagged histone binding domains, including chromodomains and bromodomains, which can be used in a variety of downstream applications.

Shop Histone Binding Domains

EpiCypher histone PTM binding domains

Bromodomain Proteins : Histone Acetylation
YEATS Proteins : Histone Acylation
Chromodomain Proteins : Histone Methylation

Learn more:

Nucleosomes vs. modified histone peptides : which is better for chromatin research? Read our Blog for more info
Interested in using nucleosomes to examine chromatin reader interactions? Click here to learn about dCypher™!

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GAS41 YEATS Domain, Recombinant Human

SKU: 15-0075

Type: YEATS Mol. Wgt.: 19.3 kDa Expressed In : E. coli Epitope Tag: His Description ...

$325.00

YEATS2 YEATS Domain, Recombinant Human

SKU: 15-0073

Type: YEATS Mol. Wgt.: 18.9 kDa Expressed In : E. coli Epitope Tag: His Description ...

$325.00

HP1β, Recombinant Human, His-Tagged

SKU: 15-0074

Type: Chromodomain Mol. Wgt.: 24.4 kDa Expressed In : E. coli Epitope Tag: 6xHis Description ...

$315.00

BRD2 Bromodomain 1

SKU: 15-0009

Type: Bromodomain Host: E. coli Mol Wgt.: 42 kDa Epitope Tag: GST Recombinant BRD2 Bromodomain 1 Description: Recombinant human BRD2 Bromodomain 1 (RING3, accession number P25440, amino...

$325.00

BRD2 Bromodomain 2

SKU: 15-0010

Type: Bromodomain Host: E. coli Mol Wgt.: 41 kDa Epitope Tag: GST Recombinant BRD2 Bromodomain 2 Description: Recombinant human BRD2 Bromodomain 2 (RING3, accession number P25440, amino...

$325.00

BRD4 Bromodomain 1

SKU: 15-0012

Type: Bromodomain Host: E. coli Mol Wgt.: 41 kDa Epitope Tag: GST Recombinant BRD4 Bromodomain 1 Description: Recombinant human BRD4 Bromodomain 1 (HUNK1, accession number O60885, amino...

$325.00

BRD4 Bromodomain 1, His-HA-Tagged

SKU: 15-0049

Type: Bromodomain Mol Wgt: 20 kDa Host: E. coli Epitope Tag: His-HA Description ...

$325.00

BRD4 Bromodomain 2, His-tagged

SKU: 15-0047

Type: Bromodomain Host: E. coli Mol Wgt.: 16 kDa Epitope Tag: His Recombinant BRD4 Bromodomain 2, His-tagged Description: Recombinant human BRD4 Bromodomain 2, His-tagged (HUNK1,...

$325.00

BRD4 Bromodomain 2

SKU: 15-0013

Type: Bromodomain Host: E. coli Mol Wgt.: 40 kDa Epitope Tag: GST Recombinant BRD4 Bromodomain 2 Description: Recombinant human BRD4 Bromodomain 2 (HUNK1, accession number O60885, amino...

$325.00

AF9 YEATS Domain, Recombinant Human

SKU: 15-0071

Type: YEATS Host: E. coli Mol Wgt.: 19.6 kDa Epitope Tag: His AF9 YEATS Domain, Recombinant Human Description: Recombinant human AF9 (MLLT3, YEATS3, accession P42568, amino acids 1...

$325.00

ENL YEATS Domain, Recombinant Human

SKU: 15-0069

Type: YEATS Host: E. coli Mol Wgt.: 19 kDa Epitope Tag: His ENL YEATS Domain, Recombinant Human Description: ENL YEATS Domain, Recombinant Human (MLLT1, LTG19, YEATS1, accession...

$325.00

ENL YEATS Domain, Y78A, Recombinant Human

SKU: 15-0070

Type: YEATS Host: E. coli Mol Wgt.: 19 kDa Epitope Tag: His ENL YEATS Domain, Y78A, Recombinant Human Description: ENL YEATS Domain, Y78A, Recombinant Human (MLLT1, LTG19, YEATS1,...

$325.00

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