<div class="snap-chik-content"> <p> YEATs domains recognize histone lysine acyl PTMs, with a preference for crotonylation over acetylation <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841940/">(Li et al. Mol Cell 2016).</a> The binding activity of YEATs domain-containing proteins are of significant interest in biomedical research, as they are common targets of gene translocation and MLL-gene fusions in leukemia. EpiCypher® offers GST-tagged recombinant YEATs domains derived from AF9 and ENL, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344132/"> including domains with point mutations that lack H3K9ac binding activity. </a></p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/recombinant-histone-binding-domains/yeats-domain-proteins-1/#yeatsdms" class="button snap-chip-custom-btn">Shop YEATs Domain Proteins</a> </div> <p></p> <h5>Learn more:</h5> <ul> <li>Why use nucleosomes? <a href="/blog/peptide-or-nucleosome-dcypher-reveals-the-optimal-substrate-for-histone-ptm-analyses/">Read about it on our Blog!</a></li> <li>Interested in screening chromatin reader binding specificity?<a href="/content/documents/brochures/EpiCypher_dCypher.pdf/"> Check out our dCypher® platform!</a></li> </ul> <h5>Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/recombinant-proteins/histone-binding-domains/">All Histone Binding Domains</a></li> <li><a href="/dcypher-assay-services-for-novel-chromatin-interactions/">dCypher® Screening Services</a></li> </ul> <a name="yeatsdms"></a>

AF9 YEATS Domain, Recombinant Human
SKU: 15-0071
Type:  YEATS Host:  E. coli Mol Wgt.:  19.6 kDa Epitope Tag:  His AF9 YEATS Domain, Recombinant Human Description: Recombinant human AF9 (MLLT3, YEATS3, accession P42568, amino...
$315.00
AF9 YEATS Domain, F59A, Recombinant Human
SKU: 15-0072
Type:  YEATS Host:  E. coli Mol Wgt.:  19.6 kDa Epitope Tag:  His AF9 YEATS Domain, F59A, Recombinant Human Description: Recombinant human AF9 (MLLT3, YEATS3, accession P42568, amino...
$315.00
ENL YEATS Domain, Recombinant Human
SKU: 15-0069
Type:  YEATS Host:  E. coli Mol Wgt.:  19 kDa Epitope Tag:  His ENL YEATS Domain, Recombinant Human Description: ENL YEATS Domain, Recombinant Human (MLLT1, LTG19, YEATS1, accession...
$315.00
ENL YEATS Domain, Y78A, Recombinant Human
SKU: 15-0070
Type:  YEATS Host:  E. coli Mol Wgt.:  19 kDa Epitope Tag:  His ENL YEATS Domain, Y78A, Recombinant Human Description: ENL YEATS Domain, Y78A, Recombinant Human (MLLT1, LTG19, YEATS1,...
$315.00