BRD2 Bromodomain 1
$325.00
SKU: 15-0009
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BRD2 is a member of the BET sub-family of bromodomain-containing proteins, which also includes BRD3, BRD4 and BRDT. BET proteins have two bromodomains and an ET domain C-terminal to the second bromodomain. BRD2 has been reported to bind multiple sites of acetylation on histone H4. BRD2 is essential for mammalian development, and has been linked to Juvenile Myoclonic Epilepsy. <br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b><span class=\"Apple-style-span\" style=\"font-family: Arial; \"><span class=\"Apple-style-span\" style=\"font-size: 12pt; \"><b>Recombinant</b></span></span> BRD2 Bromodomain 1 Formulation:</b> Recombinant GST-tagged protein at 1 mg/ml in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Storage and Stability:</b> Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Application Notes:</b> Recombinant BRD2 Bromodomain 1 is useful for protein binding and screening experiments examining acetylated protein substrates.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>References:</b><br /> <br /> </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\">View technical datasheet for this product. <a href=\"/content/documents/tds/15-0009.pdf\" target=\"_new\"> <img src=\"/content/documents/tds/icon.png\" alt=\"15-0009 Datasheet\" width=\"30\" height=\"40\" /></a></span></span> </td> </tr> </tbody> </table> </td> <td> <table width=\"100%\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\"> <tbody> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0009_gel_web.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0009_gel_web.jpg\" alt=\"15-0009 Protein Gel Data\" width=\"153\" height=\"250\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><strong>Protein Gel Data:</strong> BRD2 Bromodomain 1 (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br /> <strong>(Click image to enlarge) </strong></span></span></p> <p></p> </td> </tr> </tbody> </table> </td> </tr> </tbody></table></div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$325.00","value":325,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"Recombinant Human BRD2 Bromodomain 1 for Acetyl-Lysine Binding Protein and Substrate Recognition Experiments","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":"100 µg","shipping_messages":[],"rating":0,"meta_keywords":"Recombinant Human acetyl H4 binding, acetyl lysine binding, brd 2, brd, brd2, brd-2, bromodomain containing, bromodomain, bromodomain-containing, ring3, ring, fsrg1, nat, fsh, rnf3, ring3, ring 3, kiaa9001, d6s113e, histone binding domain, lysine, histone acetylation, acetylation, histone-binding, bromodomain containing, bromodomain, bromodomain-containing, histone binding domain, lysine, histone acetylation, acetylation","show_quantity_input":1,"title":"BRD2 Bromodomain 1","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/104/980/3vId-MiA__60159.1646104349.png?c=2","alt":"BRD2 Bromodomain 1"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/104/116/Me_Peptide_Binding-1__40818.1444238475.jpg?c=2","alt":"BRD2 Bromodomain 1"}]} Pack Size: 100 μg
{"url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/brd2-bromodomain-1","add_this":[{"service":"facebook","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"options":[],"id":"104","bulk_discount_rates":[],"can_purchase":true,"meta_description":"Recombinant Human BRD2 Bromodomain 1 for Acetyl-Lysine Binding Protein and Substrate Recognition Experiments","category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/Bromodomain Proteins"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/104/980/3vId-MiA__60159.1646104349.png?c=2","alt":"BRD2 Bromodomain 1"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=104","shipping":{"calculated":true},"num_reviews":0,"weight":"0.01 LBS","custom_fields":[{"id":"20","name":"Pack Size","value":"100 μg"}],"sku":"15-0009","description":"<div><table width=\"100%\" border=\"0\" cellspacing=\"2\" cellpadding=\"2\"> <tbody> <tr valign=\"top\"> <td> <table width=\"400\" border=\"0\" cellspacing=\"1\" cellpadding=\"1\"> <tbody> <tr> <td> <table width=\"100%\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\"> <tbody> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Type: </b>Bromodomain</span></span> </td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Host: </b><em>E. coli</em></span></span> </td> </tr> <tr> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Mol Wgt.: </b>42 kDa</span></span> </td> <td align=\"left\" valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><b>Epitope Tag: </b>GST</span></span> </td> </tr> </tbody> </table> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><br /> <b><span class=\"Apple-style-span\" style=\"font-family: Arial; \"><span class=\"Apple-style-span\" style=\"font-size: 12pt; \"><b>Recombinant </b></span></span>BRD2 Bromodomain 1 Description:</b> Recombinant human BRD2 Bromodomain 1 (RING3, accession number P25440, amino acids 57 to 200) containing an N-terminal GST tag, expressed in <em>E. coli</em>. BRD2 is a member of the BET sub-family of bromodomain-containing proteins, which also includes BRD3, BRD4 and BRDT. BET proteins have two bromodomains and an ET domain C-terminal to the second bromodomain. BRD2 has been reported to bind multiple sites of acetylation on histone H4. BRD2 is essential for mammalian development, and has been linked to Juvenile Myoclonic Epilepsy. <br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b><span class=\"Apple-style-span\" style=\"font-family: Arial; \"><span class=\"Apple-style-span\" style=\"font-size: 12pt; \"><b>Recombinant</b></span></span> BRD2 Bromodomain 1 Formulation:</b> Recombinant GST-tagged protein at 1 mg/ml in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Storage and Stability:</b> Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>Application Notes:</b> Recombinant BRD2 Bromodomain 1 is useful for protein binding and screening experiments examining acetylated protein substrates.<br /> <br /> </span></span> </td> </tr> <tr> <td valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\"><b>References:</b><br /> <br /> </span></span><br /> </p> </td> </tr> <tr> <td valign=\"top\"><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 12pt; \" class=\"Apple-style-span\">View technical datasheet for this product. <a href=\"/content/documents/tds/15-0009.pdf\" target=\"_new\"> <img src=\"/content/documents/tds/icon.png\" alt=\"15-0009 Datasheet\" width=\"30\" height=\"40\" /></a></span></span> </td> </tr> </tbody> </table> </td> <td> <table width=\"100%\" border=\"0\" cellspacing=\"3\" cellpadding=\"3\"> <tbody> <tr> <td align=\"center\"><a href=\"/content/images/products/proteins/15_0009_gel_web.jpg\" target=\"_new\"> <img src=\"/content/images/products/proteins/15_0009_gel_web.jpg\" alt=\"15-0009 Protein Gel Data\" width=\"153\" height=\"250\" /></a> </td> </tr> <tr> <td align=\"left\" valign=\"top\"> <p><span style=\"font-family: Arial; \" class=\"Apple-style-span\"><span style=\"font-size: 10pt; \" class=\"Apple-style-span\"><strong>Protein Gel Data:</strong> BRD2 Bromodomain 1 (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br /> <strong>(Click image to enlarge) </strong></span></span></p> <p></p> </td> </tr> </tbody> </table> </td> </tr> </tbody></table></div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$325.00","value":325,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"Recombinant Human BRD2 Bromodomain 1 for Acetyl-Lysine Binding Protein and Substrate Recognition Experiments","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":"100 µg","shipping_messages":[],"rating":0,"meta_keywords":"Recombinant Human acetyl H4 binding, acetyl lysine binding, brd 2, brd, brd2, brd-2, bromodomain containing, bromodomain, bromodomain-containing, ring3, ring, fsrg1, nat, fsh, rnf3, ring3, ring 3, kiaa9001, d6s113e, histone binding domain, lysine, histone acetylation, acetylation, histone-binding, bromodomain containing, bromodomain, bromodomain-containing, histone binding domain, lysine, histone acetylation, acetylation","show_quantity_input":1,"title":"BRD2 Bromodomain 1","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/104/980/3vId-MiA__60159.1646104349.png?c=2","alt":"BRD2 Bromodomain 1"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/104/116/Me_Peptide_Binding-1__40818.1444238475.jpg?c=2","alt":"BRD2 Bromodomain 1"}]} Pack Size: 100 μg
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