<div class="snap-chik-content"> <p> EpiCypher dNucs™ are semi-synthetic recombinant nucleosomes, containing one (or more) histone PTMs. Nucleosomes are the natural target of chromatin readers and modifying enzymes, and thus provide a superior substrate for epigenetic enzymes and interactor proteins</p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/nucleosomes/modified-recombinant-nucleosomes-dnucs/#dnucsprods" class="button snap-chip-custom-btn">Shop dNucs</a> <a href= https://www.epicypher.com/dnucs-small/ class="button snap-chip-custom-btn">dNuc Smaller Pack Sizes</a> </div> <p></p> <h5> dNuc substrates enable cutting-edge chromatin research </h5> <p> EpiCypher has an extensive library of >70 uniquely modified dNucs, useful for:<p> <ul> <li><a href="/dcypher-assay-services-for-novel-chromatin-interactions/">dCypher®</a>: Discovery platform to study chromatin readers and enzymes</li> <li> <a href="/content/documents/technotes/SET8_AlphaNuc.pdf/">AlphaNuc™</a>: HTS assays for inhibitor development</li> <li><a href="/epidyne-chromatin-remodeling-substrates/">EpiDyne®</a>: Quantitative chromatin remodeling assays</li> <li>Interested? Use the promo code "4for3" to buy any 3 full size dNucs and get one free!</li> </ul> <h5>Learn more:</h5> <ul> <li><a href="/content/documents/brochures/rnucs.pdf/">Recombinant Nucleosomes Brochure</a></li> <li>Using dNucs to study chromatin readers or PTM binding specificity? <a href="/content/documents/technotes/dCypher_TechNote.pdf/">See our dCypher Tech Note!</a></li> <li>Interested in inhibitor screening? <a href="/content/documents/technotes/SET8_AlphaNuc.pdf/">See our Tech Note AlphaNuc HTS assays</a></li> </ul> <h5> Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/recombinant-nucleosomes/">All Nucleosomes </a></li> <li><a href="/nucleosomes/dcypher-nucleosome-panels/">dCypher® Nucleosome Panels</a></li> </ul> <a name="dnucsprods"></a>

Nucleosome, Recombinant Human, H2AK119ub dNuc, Biotinylated
SKU: 16-0363
Nucleosome, Recombinant Human, H2AK119ub, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H2AR3me1 dNuc, Biotinylated
SKU: 16-0359
Nucleosome, Recombinant Human, H2AR3me1 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H2AR3me2a dNuc, Biotinylated
SKU: 16-0360
Nucleosome, Recombinant Human, H2AR3me2a dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H2AR3me2s dNuc, Biotinylated
SKU: 16-0361
Nucleosome, Recombinant Human, H2AR3me2s dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H2AXS139phos dNuc, Biotinylated
SKU: 16-0366
Nucleosome, Recombinant Human, H2AXS139phos dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2AX, H2B, H3 and H4; accession numbers: H2AX-P16104; H2BO60814; H3...
$575.00
Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated
SKU: 16-0372
Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated Description:Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3*;...
$575.00
Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated
SKU: 16-0373
Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3*;...
$575.00
Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated
SKU: 16-0364
Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K27acS28phos dNuc, Biotinylated
SKU: 16-0385
Nucleosome, Recombinant Human, H3K27acS28phos dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3...
$575.00
Nucleosome, Recombinant Human, H3K27bu dNuc, Biotinylated
SKU: 16-0384
Nucleosome, Recombinant Human, H3K27bu dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K27cr dNuc, Biotinylated
SKU: 16-0383
Nucleosome, Recombinant Human, H3K27cr dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3*;...
$575.00
Nucleosome, Recombinant Human, H3K36ac dNuc, Biotinylated
SKU: 16-0378
Nucleosome, Recombinant Human, H3K36ac dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated
SKU: 16-0367
Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K79me2 dNuc, Biotinylated
SKU: 16-0368
Nucleosome, Recombinant Human, H3K79me2 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated
SKU: 16-0369
Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$575.00
Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated
SKU: 16-0371
Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3*;...
$575.00
Nucleosome, Recombinant Human, H3R17me1 dNuc, Biotinylated
SKU: 16-0382
Nucleosome, Recombinant Human, H3R17me1 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3*;...
$575.00