Modified Designer Nucleosomes (dNucs™)

EpiCypher dNucs™ are semi-synthetic recombinant nucleosomes, containing one (or more) histone PTMs. Nucleosomes are the natural target of chromatin readers and modifying enzymes, and thus provide a superior substrate for epigenetic enzymes and interactor proteins.

Shop dNucs dNuc Smaller Pack Sizes

dNuc substrates enable cutting-edge chromatin research

EpiCypher has an extensive library of >70 uniquely modified dNucs, useful for:

dCypher™: Discovery platform to study chromatin readers and enzymes
AlphaNuc™: HTS assays for inhibitor development
EpiDyne®: Quantitative chromatin remodeling assays
Interested? Use the promo code "4for3" to buy any 3 full size dNucs and get one free!

Learn more:

Recombinant Nucleosomes Brochure
Using dNucs to study chromatin readers or PTM binding specificity? See our dCypher Tech Note!
Interested in inhibitor screening? See our Tech Note AlphaNuc HTS assays
How do we quantify our nucleosomes? See our Nucleosome Quantification Method

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Species: Human Source: E. coli & synthetic DNA Tag: Biotinylated Molecular Weight: 199,770.3 Da Description ...

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SKU: 16-0332

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Nucleosome, Recombinant Human, H4K20me3 dNuc, Biotinylated

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