SNAP-ChIP®: Sample Normalization and Antibody Profiling for ChIP

SNAP-ChIP uses DNA barcoded recombinant designer nucleosomes (dNucs) as next-generation spike-ins for Chromatin Immunoprecipitation (ChIP). The first product in this family (our K-MetStat, or lysine-methylation status panel) consists of a pool of dNucs carrying fifteen well-studied histone lysine methyl marks and an unmodified control. EpiCypher's K-MetStat panel can easily be added to any ChIP workflow without altering the protocol. However, users can monitor antibody specificity and evaluate technical variability within a ChIP or ChIP-seq experiment for the first time, setting SNAP-ChIP apart from any other spike-in controls (i.e. Drosophila) currently available.

SNAP-ChIP Workflow
SNAP-ChIP K-MetStat Panel
SNAP-ChIP K-MetStat Panel Description: A panel of distinctly modified mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3.1-P68431 or...
$349.00
SNAP-ChIP OncoStat Panel
SNAP-ChIP OncoStat Panel Description: A panel of distinctly modified mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3.3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3.3-P84243*;...
$349.00
Histone H3 K27me1 Antibody, SNAP-ChIP Certified
Type:  Polyclonal Host:  Rabbit Mol Wgt.:  15 kDa Appl.:  IF, WB Format:  Aff. Pur. IgG Reactivity: ChIP, ChIP-Seq, IF, IHC, WB Histone H3K27me1 Antibody Description: Rabbit...
$399.00
Histone H3K4me3 Antibody, SNAP-ChIP Certified
Type:  Monoclonal Host:  Rabbit Mol Wgt.:  15 kDa Appl.:  ChIP, ChIP-Seq, ELISA Format:  Aff. Pur. IgG Reactivity: H, M, WR Histone H3K4me3 Antibody - SNAP ChIP Certified...
$399.00
Histone H3K9me1 Antibody, SNAP-ChIP Certified
Type:  Monoclonal Host:  Rabbit Mol Wgt.:  15 kDa Appl.:  ChIP, ChIP-Seq, IF, ICC, WB Format:  Aff. Pur. IgG Reactivity: H, M, WR Histone H3K9me1 Antibody, SNAP-ChIP...
$399.00