<div class="snap-chik-content"> <p>Somatic mutations in histone proteins occur in diverse cancer types, but have been challenging to study in a physiological context. EpiCypher’s oncogenic nucleosomes (oncoNucs) are assembled with histones containing mutations specifically associated with cancer, thus providing highly relevant nucleosomal substrates for cancer research.</p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/nucleosomes/oncogenic-nucleosomes-onconucs/#onconucsprods" class="button snap-chip-custom-btn">Shop oncoNucs</a> </div> <p></p> <h5>Advancing cancer research with oncoNucs</h5> <ul> <li>Study effects of mutations on enzyme activity</li> <li>Use as substrates for testing for drug / inhibitors</li> <li>Suitable for high-throughput screening</li> </ul> <h5>Learn more:</h5> <ul> <li><a href="/content/documents/brochures/rnucs.pdf/">Recombinant Nucleosomes Brochure</a></li> <li>Nucleosomes vs. modified histone peptides : Which is best? <a href="/blog/peptide-or-nucleosome-dcypher-reveals-the-optimal-substrate-for-histone-ptm-analyses/">Read our Blog for more info!</a></li> <li>How can nucleosomes be used to study chromatin readers? <a href="/content/documents/technotes/dCypher_TechNote.pdf/">See our dCypher® Tech Note</a></li> </ul> <h5>Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/recombinant-nucleosomes/"> All Nucleosomes</a></li> <li><a href="/nucleosomes/dcypher-nucleosome-panels/">dCypher® Nucleosome Panels</a></li> </ul> <a name="onconucsprods"></a>

Mononucleosomes (H3.3K4M), Recombinant Human Biotinylated
SKU: 16-0349
Mononucleosomes (H3.3 K4M), Recombinant Human Biotinylated Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 4, expressed in E. coli. Histone H3 is one of the four proteins that are...
$470.00
Mononucleosomes (H3.3K9M), Recombinant Human Biotinylated
SKU: 16-0350
Mononucleosomes (H3.3 K9M), Recombinant Human Biotinylated Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 9, expressed in E. coli. Histone H3 is one of the four proteins that are...
$470.00
Mononucleosomes (H3.3 K27M), Recombinant Human
SKU: 16-0323
Mononucleosomes (H3.3 K27M), Recombinant Human Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 27, expressed in E. coli. Histone H3 is one of the four proteins that are...
$420.00
Mononucleosomes (H3.3 K27M), Recombinant Human Biotinylated
SKU: 16-1323
Mononucleosomes (H3.3K27M), Recombinant Human, Biotinylated: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 27, expressed in E. coli. Histone H3 is one of the four proteins...
$470.00
Mononucleosomes (H3.3G34V), Recombinant Human Biotinylated
SKU: 16-0347
Mononucleosomes (H3.3 G34V), Recombinant Human Biotinylated Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 4, expressed in E. coli. Histone H3 is one of the four proteins that are...
$470.00
Mononucleosomes (H3.3G34W), Recombinant Human Biotinylated
SKU: 16-0348
Mononucleosomes (H3.3 G34W), Recombinant Human Biotinylated Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 4, expressed in E. coli. Histone H3 is one of the four proteins that are...
$470.00
Mononucleosomes (H3.3K36M), Recombinant Human Biotinylated
SKU: 16-0344
Mononucleosomes (H3.3 K36M), Recombinant Human Biotinylated Description: Recombinant human histone H3.3 (H3F3A, H3.3A, H3F3, accession P84243) containing a methionine at position 36, expressed in E. coli. Histone H3 is one of the four proteins that...
$575.00