Histone H2AZ.1, Recombinant Human Description: Recombinant human histone H2AZ.1 (H2A.Z; H2AFZ; P0C0S5) expressed in E. coli and purified by FPLC. Histone variants H2AZ.1 and H2AZ.2 (H2A.V; H2AF.V; Q71UI9) differ by three amino acids and are incorporated into a subset of nucleosomes in place of canonical histone H2A. H2AZ is implicated in diverse functions ranging from transcriptional regulation, chromosome transmission and DNA damage repair. H2AZ has a dedicated deposition machinery (the SWR-C ATPase) and is acetylated by the KAT5/TIP60 complex.
Histone H2AZ.1, Recombinant Human Formulation: 100 µg of lyophilized powder.
Histone H2AZ.1, Recombinant Human Storage and Stability: Lyophilized proteins are stable for 2 years at -20°C from date of shipment. Reconstitute with sterile distilled water and aliquot to avoid repeated freezing and thawing. Stable for 6 months at -80°C after reconstitution.
Histone H2AZ.1, Recombinant Human Application Notes: Recombinant histone H2AZ.1 is suitable for enzyme assays and nucleosome reconstitution.
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QC Purity Data: Histone H2AZ.1, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated. (Click image to enlarge)