Improved controls for CUT&RUN profiling of epitope-tagged proteins
Protein tags have multiple uses and advantages in molecular biology1,2. They can improve protein stability in vitro, streamline purification processes, […]
Antibodies
How to select the best histone PTM antibody for CUT&RUN and CUT&Tag
EpiCypher’s CUTANA™ CUT&RUN and CUT&Tag technologies are enabling major advancements in high-resolution profiling of histone post-translational modifications (PTMs) across scientific disciplines, including immunology, neuroscience,
Chromatin Mapping Basics: ChIP-seq
Even if you are new to epigenetics, you have probably heard of ChIP-seq, CUT&RUN, and CUT&Tag – but how do these assays
Starting CUT&RUN or CUT&Tag for a new target – What you need to know
CUT&RUN and CUT&Tag are ultra-sensitive chromatin mapping technologies gaining widespread popularity in the epigenomics field. These streamlined approaches are compatible
New CUTANA-compatible antibodies pave the way to study transcription factors and chromatin-interacting proteins with CUT&RUN
EpiCypher recently launched CUTANA™ CUT&RUN assays, which generate high quality chromatin profiling data with reduced cell inputs and sequencing requirements compared with
Defined Spike-in Controls and a Validated Workflow for our New CUT&RUN Kits
CUT&RUN is quickly becoming a leading assay for chromatin profiling, and it’s easy to see why. The targeted cleavage of
Choosing the Right ChIP Antibody for Your Experiment
There are multiple components to designing and executing a successful chromatin immunoprecipitation (ChIP) or ChIP-seq experiment: – What target should
Antibodies, ChIP-seq, Nucleosome
Histone Peptides vs. Nucleosomes : Which is better for ChIP antibody validation?
Highly specific antibodies are a crucial component of epigenetics research, and form the foundation of multiple chromatin profiling assays. For