Exploring Drug Mechanism of Action with CUT&RUN Services: Q&A with Foghorn Therapeutics
Disruption of epigenetic mechanisms can lead to abnormal gene expression and is linked to many diseases, including cancer, inflammation, and […]
A Comprehensive Guide to DNA Methylation Sequencing Methods
DNA methylation is a critical epigenetic modification with profound implications on gene regulation, development, and disease research. As interest in epigenomics
4 CUT&RUN and CUT&Tag applications to inspire your research in 2025
CUT&RUN and CUT&Tag are powerful chromatin mapping tools driving innovative research. Over the years, we have written comprehensive blog posts comparing
Looking to boost your drug discovery and development pipelines? Here’s how
Thoroughly understanding disease mechanisms is key to successful drug discovery and development. Chromatin structure plays a significant role in disease
Explore new genomic applications with multiomic CUT&Tag
Multiomic studies, which involve the integration of DNA, RNA, and protein “omics” datasets from a single cell or sample type,
Revolutionizing epigenomics with single-cell CUT&Tag
Single-cell epigenomics has transformed our understanding of cellular diversity and gene regulation. By analyzing individual cells, researchers can uncover the
SPRI bead or column DNA purification: Which method is best for CUT&RUN?
Purification of target-enriched DNA is central to CUT&RUN (and CUT&Tag) chromatin mapping workflows. When considering a DNA cleanup strategy, multiple
What’s new with CUT&Tag? Seven FAQs you need to read
From single cell profiling and spatial epigenomics to analysis of FFPE samples, CUT&Tag is making headlines1-7. CUT&Tag is also a
Webinar recap: Nucleosomes define the histone code
At the center of chromatin regulatory mechanisms is the nucleosome – a histone octamer wound by DNA. The tails of
Improved controls for CUT&RUN profiling of epitope-tagged proteins
Protein tags have multiple uses and advantages in molecular biology1,2. They can improve protein stability in vitro, streamline purification processes,