SKU: 13-0012
Size/Quantity: 100 µL

Symmetric Dimethyl-arginine Antibody (SDMA) Sym10

$385.00

9 in stock

Symmetric dimethylation of arginine (sDMA) is a post-translational modification catalyzed by type II arginine methyltransferase enzymes and found on many proteins,including those involved in transcriptional regulation, mRNA splicing, DNA repair and nuclear transport. Sym10 recognizes SDMA present at GAR (glycine-arginine rich sequences).

  • Type: Polyclonal
  • Mol Wgt.: N/A
  • Format: Serum
  • Host: Rabbit
  • Appl.: WB
  • Reactivity: H, M

Immunogen
KLH-conjugated peptide with the sequence KRGRGRGRG in which arg residues were symmetrically dimethylated.

Formulation
Rabbit serum with 30% glycerol and 0.035% sodium azide.

Storage and Stability
Stable for 2 years at -20°C from date of receipt.
 

Application Notes
Sym10 antibody is useful for Western blotting (1:500 – 1:2,000 dilution) to detect SDMA on a variety proteins.

References
Boisvert FM et al (2002) J Cell Biol 159: 957-969. Link
Boisvert FM et al (2003) Mol Cell Proteom 2: 1319-1330. Link
C̫te J et al (2005). J Biol Chem 280: 28476-28483. Link
Deng X et al (2010). PNAS USA 107: 19114?19119. Link
Jung GA et al (2011). Exp Mol Med 43:550-560. Link

Technical Datasheet

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