EpiDyne Remodeling Assay Substrate DNA ST601-GATC0, Biotinylated

EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which has high affinity for histone octamers and is useful for nucleosome assembly. The DNA also includes a 3’ acceptor sequence to accommodate the histone octamer subsequent to remodeling and a 5’ biotin-TEG group. This negative control does not contain DpnII restriction sites. When paired with the positive control DNA (EpiCypher 18-4111) these controls illustrate the migration range for the Restriction Enzyme Assay. See the EpiDyne Nucleosome Remodeling Assay Tech Note (Restriction Enzyme Assay) for more information:
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