Nucleosome, Recombinant Human, H4K16ac dNuc, Biotinylated

Recombinant mononucleosomes (H4K16ac) consist of 147 base pairs of DNA wrapped around an octamer core of histone proteins (two each of H2A, H2B, H3.1, and H4) to form a nucleosome, the basic repeating unit of chromatin. The 147 bp 601 sequence, identified by Lowary and Widom [1], has high affinity for histone octamers and is useful for nucleosome assembly. H4K16ac contains acetyl-lysine at position 16 on histone H4. The DNA contains a 5’ biotin-TEG group.