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Featured Webinars
Browse our collection to learn more about our chromatin research technologies and how they are used to uncover gene regulatory mechanisms in diverse research applications, including cancer, immunology, drug development, and more.
Hosted by Fragile Nucleosome, Dr. Michael-Christopher Keogh (CSO, EpiCypher) presents on the development of automated CUT&RUN and high-specificity, ultra-efficient histone PTM antibodies which were essential to map the landscape of the mouse immune system (>2,200 automated CUT&RUN profiles of eight targets; each in 10k nuclei from ~100 distinct cell types).
Unlock Chromatin Insights with CUTANA™ CUT&RUN – Best Tips & Tricks
Tessa Firestone (Research Assoicate, EpiCypher) explores why CUT&RUN is a leading epigenetics method for drug discovery and impact studies, and how EpiCypher’s CUTANA™ CUT&RUN delivers reliable, easy-to-use results. Learn key tips for protocol fundamentals, reagent selection, sample prep, and data analysis.
Learn More: Fiber-seq (LRS)
Fiber-seq is a multiomic long-read sequencing (LRS) assay that simultaneously profiles chromatin accessibility, DNA methylation, protein footprints, and genetic variants at single-molecule resolution. LRS is redefining how researchers study the epigenome by directly capturing genetic and epigenetic features from single DNA molecules. Unlike short-read methods, LRS resolves chromatin features genome-wide, even within highly repetitive and structurally complex genomic regions, while also enabling haplotype phasing. EpiCypher is pioneering complete solutions for long-read sequencing-based epigenomics, starting with Fiber-seq.
Fiber-seq: Removing barriers to long-read epigenomics
Hosted by PacBio, Bryan Venters (Senior Director of Genomics, EpiCypher) highlights how Fiber-seq delivers single-molecule insights into nucleosome positioning, CTCF binding, and long-range genomic interactions from one comprehensive assay.
Resolving Mendelian Diseases with Long-Read Multiome Sequencing
Dr. Andrew Stergachis (Associate Professor of Medicine and Genome Sciences, University of Washington) explains how Fiber-seq maps chromatin and noncoding variants to uncover their roles in Mendelian disorders, capturing long-range genomic changes missed by other methods.
Combining Fiber-seq and PureTarget to Discover Hidden Alterations in Genome Engineered Models
Dr. Zach Freeman (Director, Transgenic Animal Model Core, University of Michigan) shows how Fiber-seq and PacBio’s PureTarget™ enable complete mapping of transgene integration and regulation, while EpiCypher’s Dr. Emily Madden (Product Manager) shares practical tips and applications for getting started with Fiber-seq.
Learn More: CUT&RUN and CUT&Tag
CUTANA™ Assays for CUT&RUN and CUT&Tag are redefining epigenomic profiling through highly sensitive, low-input workflows. These optimized assays enable robust chromatin mapping from limited cell numbers and challenging targets, expanding capabilities for clinical research and other limited or hard-to-analyze samples.
Decoding Drug Mechanism of Action with Chromatin Mapping Assays
Hosted by GEN, Dr. Dave Lahr (Sr. Director of Bioinformatics, Foghorn Therapeutics) presents on how chromatin mapping tools like CUT&RUN and CUTANA™ reveal drug mechanisms of action and accelerate drug discovery through actionable epigenomic insights.
HER2-ER Nuclear Crosstalk in Triple-Positive Breast Cancer
Hosted by The Scientist’s, Dr. Rebecca Riggins (Professor, Georgetown Cancer Center) presents on how CUT&RUN chromatin mapping provides new insights into triple-positive breast cancer and accelerates cancer research.
Unlock Chromatin Insights with CUTANA™ CUT&RUN – Best Tips & Tricks
Tessa Firestone (Research Assoicate, EpiCypher) explores why CUT&RUN is a leading epigenetics method for drug discovery and impact studies, and how EpiCypher’s CUTANA™ CUT&RUN delivers reliable, easy-to-use results. Learn key tips for protocol fundamentals, reagent selection, sample prep, and data analysis.
Single-cell DNA Damage Analysis Reveals Selective Genome Vulnerability
Learn from guest speakers Chris Hartl (CTO, Epigenome Technologies) and Chenxu Zhu (Assistant Professor, Weill Cornell Medicine) how Paired-Damage-seq enables simultaneous profiling of oxidative DNA damage and the transcriptome. This groundbreaking single-cell multiomic method uses CUT&Tag to map DNA damage at specific genomic regions, revealing cell-type-specific damage patterns linked to epigenetic states and disease mechanisms.
Learn More: DNA Methylation
EpiCypher provides next-generation tools for DNA methylation sequencing, offering innovative alternatives to traditional bisulfite-based methods. Leveraging the CUTANA™ CUT&RUN approach, our assays deliver high-resolution, low-input DNA methylation insights—without the high cost of whole genome sequencing. We offer two distinct solutions to meet diverse research needs — meCUT&RUN & Multiomic CUT&RUN — together these assays enable powerful DNA methylation analysis across a wide range of biological contexts.
Solving the Challenge of Genome-Wide DNA Methylation Sequencing: Cost vs. Coverage
Bryan Venters (EpiCypher, Sr. Director of Genomics) introduces CUTANA™ meCUT&RUN, a cost-effective, bisulfite-free approach to high-resolution, genome-wide DNA methylation profiling.
Learn More: CUTANA™ Cloud
CUTANA™ Cloud is a web platform that simplifies bioinformatic analysis of CUT&RUN and CUT&Tag data. Designed for speed, security, and ease-of-use, it rapidly aligns raw sequencing files to quickly determine the success of an experiment. Analysis of epigenomic data can be a major bottleneck, delaying experimental validation and slowing the path to biological insights. This platform eliminates these challenges, providing an accessible solution for every researcher — no coding required.
From Bench to Browser: Unlocking CUT&RUN and CUT&Tag analysis with CUTANA™ Cloud
Dr. Keith Maier (Associate Director of Product Development, EpiCypher) introduces CUTANA™ Cloud, a user-friendly platform for analyzing CUT&RUN and CUT&Tag data, automating alignment, peak calling, and QC to deliver publication-ready results without coding.