CUTANA Concanavalin A-Conjugated Paramagnetic Beads – 50 Reactions (550 µL)
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- 550 µL - 50 Reactions
- 2.75 mL - 250 Reactions
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Powered by BiozAvailable in 50 and 250 Reaction pack sizes. This product contains Concanavalin A (ConA) conjugated to paramagnetic microspheres. ConA is a lectin (carbohydrate-binding protein) that binds specifically to mannosyl- and glucosyl-containing extracellular glycoproteins. The ConA magnetic beads are therefore useful to immobilize cells or nuclei presenting these glycans in their extracellular matrices.
Figure 1:
CUT&RUN data was generated using EpiCypher CUTANA™ Concanavalin A-Conjugated Paramagnetic Beads (10 µL) with 500,000 K562 cells and H3K4me3 antibody (EpiCypher Catalog No. 13-0041, 1:100 dilution). Shown is a heatmap for H3K4me3 CUT&RUN signal (from 3.9 million paired-end reads) aligned to the transcription start site (TSS, +/- 2kb) of 18,793 genes. High and low signal are ranked by intensity (top to bottom) and reflected by red and blue colors, respectively.
Figure 2:
H3K4me3 CUT&RUN data was generated as described above. Four representative loci are shown in the Integrative Genomics Viewer (IGV, Broad Institute). Window size is denoted at the top of each panel.