<div class="snap-chik-content"> <p> MBT domains recognize methylated lysine residues, and are structurally similar to other methyl-lysine chromatin reader domains (e.g. chromodomains). L3MBTL1 is one of the more well-characterized MBT-containing proteins, and has been studied in the context of leukemia, pluripotent stem cells, and neuronal function. EpiCypher offers GST-tagged recombinant MBT domains derived from L3MBTL1, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689580">including domains with point mutations that lack methyl-lysine binding activity.</a></p> <div class="custom-btns-block"> <a href="https://www.epicypher.com/recombinant-histone-binding-domains/mbt-domain-proteins-1/#mbtdms" class="button snap-chip-custom-btn">Shop MBT Domain Proteins</a> </div> <p></p> <h5>Learn more:</h5> <ul> <li>Why use nucleosomes?<a href="/blog/peptide-or-nucleosome-dcypher-reveals-the-optimal-substrate-for-histone-ptm-analyses/"> Read about it on our Blog!</a></li> <li>Interested in screening chromatin reader binding specificity?<a href="/content/documents/brochures/EpiCypher_dCypher.pdf/"> Check out our dCypher® platform!</a></li> </ul> <h5>Shop related products and services:</h5> <ul class="category-nav-list"> <li><a href="/recombinant-proteins/histone-binding-domains/">All Histone Binding Domains</a></li> <li><a href="/dcypher-assay-services-for-novel-chromatin-interactions/">dCypher® Screening Services</a></li> </ul> <a name="mbtdms"></a>

L3MBTL1 3xMBT Domain, Recombinant Human
SKU: 15-0043
Type:  MBT Host:  E. coli Mol Wgt.:  68 kDa Epitope Tag:  GST Recombinant L3MBTL1 3xMBT Domain Description: Recombinant human L3MBTL1 (LMBL1, KIAA0681, L3MBT, L3MBTL, accession Q9Y468, amino...
$315.00
L3MBTL1 3xMBT Domain, D355N, Recombinant Human
SKU: 15-0056
Type:  MBT Host:  E. coli Mol Wgt.:  68 kDa Epitope Tag:  GST L3MBTL1 3xMBT Domain, D355N, Recombinant Human Description: Recombinant human L3MBTL1 (LMBL1, KIAA0681, L3MBT, L3MBTL, accession...
$315.00