dNucs™ Designer Recombinant Nucleosomes for Drug Discovery Research

What are dNucs?

Nucleosomes are the only physiologically-relevant substrate for chromatin-associated enzyme and protein investigation. Designer Nucleosomes (dNucs) are human recombinant nucleosomes containing specific post–translational modifications, including lysine acetylation and lysine methylation. EpiCypher is pioneering the manufacture of this “new to the market” product family.

Why Use dNucs in Your Assays

dNucs from EpiCypher are ground breaking products that will transform your epigenetics drug discovery research. EpiCypher will add new dNucs on a continual basis. dNucs open the possibility of high content studies and experimental access to new families of epigenetic regulators. These products set the industry standard for quality and are available only from EpiCypher.
16-0010 Gel and Purity QC Data Check out EpiCypher's non-radioactive assays using dNucs and recombinant nucleosomes in histone modification and histone binding assays
16-0010 Gel and Purity QC Data Download the whitepaper describing the advantages of EpiCypher's proprietary dNuc manufacturing process
Nucleosome, Recombinant Human, H2AK119ub dNuc, Biotinylated
Nucleosome, Recombinant Human, H2AK119ub, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H2AR3me1 dNuc, Biotinylated
Nucleosome, Recombinant Human, H2AR3me1 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H2AR3me2a dNuc, Biotinylated
Nucleosome, Recombinant Human, H2AR3me2a dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H2AR3me2s dNuc, Biotinylated
Nucleosome, Recombinant Human, H2AR3me2s dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H2AXS139phos dNuc, Biotinylated
Nucleosome, Recombinant Human, H2A.XS139phos dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3...
$549.00
Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K18ac dNuc, Biotinylated Description:Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K18bu dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K23ac dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K79me1 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K79me2 dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K79me2 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K79me3 dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K9bu dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H4R3me2s dNuc, Biotinylated
Nucleosome, Recombinant Human, H4R3me2s dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.1-P68431;...
$549.00
Nucleosome, Recombinant Human, H3K18cr dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K18cr dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2BO60814; H3.2-Q71DI3 *;...
$549.00
Nucleosome, Recombinant Human, H3K4,9,14,18ac dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K4,9,14,18ac dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3...
$549.00
Nucleosome, Recombinant Human, H3K4ac dNuc, Biotinylated
Nucleosome, Recombinant Human, H3K4ac dNuc, Biotinylated Description: Mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3.2- Q71DI3 *;...
$549.00