Histone H3K4Me3 antibody Description: Rabbit polyclonal antibody recognizing the histone H3 trimethylated at lysine 4. Histone H3 is one of a core components of the nucleosome, the smallest subunit of chromatin. Trimethylation of histone H3 at lysine 4 (H3K4Me3) is associated with transcriptional activation and also frequently found in the context of H3 acetylation at multiple residues.
Histone H3K4Me3 antibody Immunogen: Synthetic peptide corresponding to the amino terminus of human histone H3 trimethylated at lysine 4.
Histone H3K4Me3 antibody Formulation: Rabbit serum with 30% glycerol and 0.035% sodium azide.
Storage and Stability: Stable for 2 years at -20°C from date of receipt.
Application Notes: Histone H3K4Me3 Antibody for use in (1:500 dilution) and Western blot (1:1,000 - 1:3,500).
References: Zhang L et al (2005). EMBO J 24: 2379-2390. Link Seward DJ et al (2007). Nat Struct Mol Biol 14: 240-242. Link
View technical datasheet for this product. View additional specificity data this product.
Specificity Data: EpiGold™ Histone Peptide arrays used to analyze the histone modification specifity of Histone H3K4Me3 antibody. Data is shown for the highest reacting singly-modified peptides. For more specificity data, see Additional Peptide Array Specificity Data.
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