Recombinant Bromodomain Proteins

Bromodomain proteins are key mediators of signal transduction, recognizing acetylated lysine residues on histone and non-histone target proteins. Recognition of acetylated histones by bromodomain-containing “effector” proteins allows the recruitment of specific protein complexes to regions of acetylated chromatin. As acetylation of chromatin is correlated with higher levels of transcription, many bromodomain proteins are involved in transcriptional activation and the opening of chromatin structure. Recombinant bromodomain proteins are useful for determining substrate recognition and for use in acetyl-lysine binding experiments.

EpiCypher bromodomains are highly purified and GST-tagged. We are constantly in the process of adding new products. If you dont see what you are looking for, come back in a few days or inquire at info@epicypher.com.

For more information:      Sanchez R and MM Zhou (2009). The role of human bromodomains in chromatin biology and gene transcription. Curr Opin Drug Discov Devel. 12: 659–665. PUBMED      Filippakopoulos P and S Knapp (2012). The bromodomain interaction module. FEBS Lett. 14: 2692-2704. PUBMED

NEW! BRD4 AlphaLISA™ Reader Domain Assays

ACF1 / BAZ1A Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  39 kDa Epitope Tag:  GST Recombinant ACF1 / BAZ1A Bromodomain Description: Recombinant human ACF1 Bromodomain (BAZ1A, WCRF180, accession Q9NRL2,...
$299.00
BATZFD Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  38 kDa Epitope Tag:  GST Recombinant BATZFD Bromodomain Description: Recombinant human BATZFD Bromodomain (Bromodomain adjacent to zinc finger...
$299.00
BAZ2B Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  39 kDa Epitope Tag:  GST Recombinant BAZ2B Bromodomain Description: Recombinant human BAZ2B Bromodomain (WALp4, accession Q9UIF8, amino acids...
$299.00
BPTF Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  40 kDa Epitope Tag:  GST Recombinant BPTF Bromodomain Description: Recombinant human BPTF (FAC1, FALZ, accession number Q12830, amino acids 2925...
$299.00
BRD2 Bromodomain 1
Type:  Bromodomain Host:  E. coli Mol Wgt.:  42 kDa Epitope Tag:  GST Recombinant BRD2 Bromodomain 1 Description: Recombinant human BRD2 Bromodomain 1 (RING3, accession number P25440, amino...
$299.00
BRD2 Bromodomain 2
Type:  Bromodomain Host:  E. coli Mol Wgt.:  41 kDa Epitope Tag:  GST Recombinant BRD2 Bromodomain 2 Description: Recombinant human BRD2 Bromodomain 2 (RING3, accession number P25440, amino...
$299.00
BRD3 Bromodomain 1
Type:  Bromodomain Host:  E. coli Mol Wgt.:  41 kDa Epitope Tag:  GST Recombinant BRD3 Bromodomain 1 Description: Recombinant human BRD3 Bromodomain 1 (RING3L, accession number Q15059, amino...
$299.00
BRD3 Bromodomain 2, Recombinant Human
Type:  BromodomainHost:  E. coliMol Wgt.:  41 kDaEpitope Tag:  GST BRD3 Bromodomain 2, Recombinant Human Description: Recombinant human BRD3 Bromodomain 2 (RING3L, accession number Q15059, amino acids 25 to 160)...
$299.00
BRD4 Bromodomain 1
Type:  Bromodomain Host:  E. coli Mol Wgt.:  41 kDa Epitope Tag:  GST Recombinant BRD4 Bromodomain 1 Description: Recombinant human BRD4 Bromodomain 1 (HUNK1, accession number O60885, amino...
$299.00
BRD4 Bromodomain 1, His-tagged
Type:  Bromodomain Host:  E. coli Mol Wgt.:  18 kDa Epitope Tag:  His Recombinant BRD4 Bromodomain 1, His-tagged Description: Recombinant human BRD4 Bromodomain 1, His-tagged (HUNK1,...
$299.00
BRD4 Bromodomain 2
Type:  Bromodomain Host:  E. coli Mol Wgt.:  40 kDa Epitope Tag:  GST Recombinant BRD4 Bromodomain 2 Description: Recombinant human BRD4 Bromodomain 2 (HUNK1, accession number O60885, amino...
$299.00
BRD4 Bromodomain 2, His-tagged
Type:  Bromodomain Host:  E. coli Mol Wgt.:  16 kDa Epitope Tag:  His Recombinant BRD4 Bromodomain 2, His-tagged Description: Recombinant human BRD4 Bromodomain 2, His-tagged (HUNK1,...
$299.00
BRD7 Bromodomain, Recombinant Human
Type:  BromodomainHost:  E. coli Mol Wgt.:  37 kDaEpitope Tag:  by product BRD7 Bromodomain, Recombinant Human Description: BRD7 Bromodomain, Recombinant Human...
$299.00
BRD9 Bromodomain, Recombinant Human
Type:  BromodomainHost:  E. coli Mol Wgt.:  37 kDa Epitope Tag:  GST BRD9 Bromodomain, Recombinant Human Description: BRD9 Bromodomain,...
$299.00
BRDT Bromodomain 2
Type:  Bromodomain Host:  E. coli Mol Wgt.:  38 kDa Epitope Tag:  GST Recombinant BRDT Bromodomain 2 Description: Recombinant human BRDT bromodomain 2 (CT9, Fsrg3, accession number Q58F21,...
$299.00
BRG1 / SMCA4 Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  41 kDa Epitope Tag:  GST Recombinant BRG1 / SMCA4 Bromodomain Description: Recombinant human BRG1 Bromodomain (Brahma-related gene 1, SMC4A,...
$299.00
CBP Bromodomain
Type:  Bromodomain Host:  E. coli Mol Wgt.:  36 kDa Epitope Tag:  GST Recombinant CBP Bromodomain Description: Recombinant human CBP Bromodomain (CREB Binding protein, CREBBP, accession...
$299.00
CBP Bromodomain, His-Tagged
Type:  Bromodomain Host:  E. coli Mol Wgt.:  12 kDa Epitope Tag:  His Recombinant CBP Bromodomain, His-Tagged Description: Recombinant human CBP Bromodomain, His-Tagged (CREB Binding...
$299.00