SNAP-ChIP^® Spike-ins

SNAP-ChIP^® Spike-in panels use modified DNA-barcoded Designer Nucleosomes (dNucs™) carrying disease-relevant histone PTMs as quantitative controls and for antibody validation, enabling unprecedented control of ChIP experiments.

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Three ways SNAP-ChIP spike-ins improve ChIP

Identify and/or validate PTM-specific antibody (see our recent paper in Molecular Cell)
In situ monitoring of ChIP performance (read our Blog for more)
Quantitative normalization (click here and here for some great examples!)

Learn more:

Learn the basics of SNAP-ChIP Spike-ins here!
SNAP-ChIP Brochure
Why should you use SNAP-ChIP for antibody validation? Read our feature at Nature.com.
How can SNAP-ChIP spike-ins improve ChIP? Read about it on the EpiCypher Blog!
How do we quantify our nucleosomes? See our Nucleosome Quantification Method

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SNAP-ChIP® K-AcylStat Panel

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SNAP-ChIP® OncoStat Panel

SNAP-ChIP OncoStat Panel Description: A panel of distinctly modified mononucleosomes assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3.3 and H4; accession numbers: H2A-P04908; H2B-O60814; H3...

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SNAP-ChIP® K-MetStat Panel

SNAP-ChIP® K-AcylStat Panel

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