Nucleosome Components and Subunits

Many scientists need distinct nucleosome components for their own custom nucleosome assembly experiments. EpiCypher is pleased to offer recombinant subunits of nucleosomes, including histone octamers, H3/H4 tetramers, H2A/H2B dimers, and Widom 601 nucleosome assembly DNA.

Shop Nucleosome Components and Subunits

The building blocks of nucleosomes

Controls for the study of histone proteoforms in mass spectrometry (Fouque et al. 2022)
Building arrays of Widom 601 DNA for nucleosome reconstitution (Spakman et al. 2020)
Assembly of CENP-A variant nucleosomes (Stumme-Diers et al. 2019)

Learn more:

Nucleosomes are important substrates for chromatin research - read our blog for more info
If we don’t offer the nucleosome you need, consider our custom nucleosome assembly services
dCypher nucleosome binding assays are advancing medical research: learn more

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EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0, Biotinylated

SKU: 18-4110

Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...

$115.00

Nucleosome Assembly 601 Sequence DNA, 199 bp, Biotinylated

SKU: 18-2044

Description Nucleosome Assembly 601 Sequence DNA, 199 bp, Biotinylated is a double-stranded DNA fragment with 26 bp linkers on either end of a 147 bp 601 Widom sequence, identified by Lowary...

$115.00

Nucleosome Assembly 601 Sequence DNA

SKU: 18-0006

Description Nucleosome Assembly 601 Sequence DNA is a 147 base-pair double-stranded DNA fragment that was identified by Lowary and Widom using the SELEX method [1]. The 601...

$115.00

Histone Octamer (H4 ΔN15), Recombinant Human

SKU: 16-8018

Type a description for this product here...

$215.00

Histone Octamer (H3.1 ΔN32), Recombinant Human

SKU: 16-8016

Type a description for this product here...

$215.00

Histone Octamer (H3.3), Human Recombinant

SKU: 16-8012

Histone Octamer (H3.3), Human Recombinantt Description: Human histone octamers assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3.3 and H4; accession numbers: H2A-P04908;...

$215.00

Histone Octamer, Recombinant Human

SKU: 16-0001

Species: Human Source: E. coli Tag: None Molecular Weight: 108,545 Da Description ...

$215.00

Nucleosome Assembly 601 Sequence DNA, Biotinylated

SKU: 18-0005

Description Nucleosome Assembly 601 Sequence DNA is a 147 base-pair double-stranded DNA fragment that was identified by Lowary and Widom using the SELEX method [1]. The 601...

$115.00

EpiDyne® Remodeling Assay Substrate DNA ST601-GATC0

SKU: 18-4100

EpiDyne Remodeling Assay Substrate DNA ST601-GATC0 Description: EpiDyne Remodeling Assay Substrate DNA...

$115.00

EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1

SKU: 18-4101

Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...

$115.00

EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1, Biotinylated

SKU: 18-4111

Description EpiDyne® Remodeling Assay Substrate DNA ST601-GATC1 is a 217 base-pair double-stranded DNA fragment containing the 601 nucleosome positioning sequence [1], which...

$115.00

Histone H2A/H2B Dimer, Recombinant Human

SKU: 15-0311

Type: Histone Host: E. coli Mol Wgt.: 29 kDa Epitope Tag: by product Histone H2A/H2B Dimers, Recombinant Human Description: Histone H2A/H2B dimers made from recombinant histones...

$165.00

Histone H3/H4 Tetramer, Recombinant Human

SKU: 16-0008

Type: Histone Host: E. coli Mol Wgt.: 54 kDa Epitope Tag: by product Histone H3/H4 Tetramers, Recombinant Human Description: Histone H3/H4 Tetramers made from recombinant histones...

$160.00

Histone CENP-A / H4 Tetramer, Recombinant Human

SKU: 16-0010

Type: Histone Host: E. coli Mol Wgt.: 54 kDa Epitope...

$160.00

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