Recombinant CECR2 Bromodomain Description: Recombinant human CECR2 Bromodomain (Cat eye syndrome critical region protein 2, accession number Q9BXF3, amino acids 421 to 550) containing an N-terminal GST tag, expressed in E. coli. CECR2 is a member of the CERF chromatin remodeling complex, also containing SNF2L / SMARCA1. The bromodomain from CECR2 binds several sites of histone acetylation on H2A, H2B and H3. The CECR2 gene a candidate for Cat Eye Syndrome, a developmental defect resulting from a duplication of the region of chromosome 22 that contains CECR2.
Recombinant CECR2 Bromodomain Formulation: Recombinant GST-tagged protein at 1 mg/ml in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol.
Storage and Stability: Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Application Notes: Recombinant CECR2 Bromodomain is useful for protein binding and screening experiments examining acetylated protein substrates.
View technical datasheet for this product.
Protein Gel Data: CECR2 Bromodomain (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated. (Click image to enlarge)