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EpiCypher

CBP Bromodomain, His-Tagged

Cat. No.: 15-0048
List Price: $299.00
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Product Description

Type:  Bromodomain Host:  E. coli
Mol Wgt.:  12 kDa Epitope Tag:  His

Recombinant CBP Bromodomain, His-Tagged Description: Recombinant human CBP Bromodomain, His-Tagged (CREB Binding protein, CREBBP, accession number Q92793, amino acids 1091 to 1190) containing an N-terminal His-tag, expressed in E. coli. CBP is an important regulator of cell function and serves to integrate a number of key cell signaling pathways. CBP contains intrinsic histone acetylatransferase (HAT) activity and serves as a co-activator for a large number of transcription factors. The bromodomain of CBP specifically recognizes a number of acetylated proteins, including histones and transcription factors. The CBP gene is mutated in Rubinestein-Taybi Syndrome, a rare developmental disorder.

Recombinant CBP Bromodomain, His-Tagged Formulation: Recombinant 6xHis-tagged protein at 1 mg/ml in 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol.

Storage and Stability: Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.

Application Notes: Recombinant CBP Bromodomain, His-Tagged is useful for protein binding and screening experiments examining acetylated protein substrates.

References:


View technical datasheet for this product. 15-0048 Datasheet
15-0048 Protein Gel Data

Protein Gel Data: CBP Bromodomain, His-Tagged (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.
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