BRD7 Bromodomain, Recombinant Human Description: BRD7 Bromodomain, Recombinant Human (Bromodomain- containing protein 7, BP75, CELTIX-1, accession number Q9NPI1, amino acids 127 - 241) containing an N-terminal GST tag, expressed in E. coli. BRD7 is part of the PBAF SWI/SNF chromatin remodeling complex. BRD7 bromodomain interacts with acetylated histone H3 (lys 9 and lys 14) and H4 (lys 8). BRD7 has been reported to function as both a co-activator and a co-repressor of transcription.
BRD7 Bromodomain, Recombinant Human Formulation: Recombinant GST-tagged protein at 1 mg/ml in 50 mM TRIS pH 7.5, 200 mM NaCl, 1 mM DTT, 20% glycerol.
BRD7 Bromodomain, Recombinant Human Storage and Stability: Lyophilized proteins are stable for 2 years at -20°C from date of shipment. Reconstitute with sterile distilled water and aliquot to avoid repeated freezing and thawing. Stable for 6 months at -80°C after reconstitution.
BRD7 Bromodomain, Recombinant Human Application Notes: BRD7 Bromodomain, Recombinant Human is useful for protein binding and screening experiments examining acetylated protein and peptide substrates.
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QC Purity Data: BRD7 Bromodomain, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated. (Click image to enlarge)